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Very widespread (may have an effect on greater than 1 in 10 people) injection site reactions (including ache, swelling, redness or itching) respiratory tract infections (including cold, runny nose, sinus an infection, pneumonia) headache abdominal pain nausea and vomiting rash musculoskeletal pain Common (may affect up to 1 in 10 people) critical infections (together with blood poisoning and influenza) intestinal infections (including gastroenteritis) skin infections (including cellulitis and shingles) ear infections oral infections (including tooth infections and cold sores) reproductive tract infections urinary tract infection fungal infections joint infections benign tumours pores and skin most cancers allergic reactions (including seasonal allergy) dehydration temper swings (together with melancholy) nervousness issue sleeping sensation disorders similar to tingling, prickling or numbness migraine nerve root compression (including low again ache and leg pain) vision disturbances eye inflammation irritation of the eye lid and eye swelling vertigo (feeling of dizziness or spinning) sensation of heart beating rapidly high blood pressure flushing haematoma (assortment of blood exterior of blood vessels) cough asthma shortness of breath gastrointestinal bleeding dyspepsia (indigestion, bloating, heart burn) acid reflux illness sicca syndrome (including dry eyes and dry mouth) itching 442 itchy rash bruising inflammation of the skin (corresponding to eczema) breaking of finger nails and toe nails increased sweating hair loss new onset or worsening of psoriasis muscle spasms blood in urine kidney problems chest ache oedema (swelling) fever reduction in blood platelets which increases danger of bleeding or bruising impaired healing Uncommon (may affect up to 1 in a hundred people) opportunistic infections (which include tuberculosis and different infections that happen when resistance to disease is lowered) neurological infections (including viral meningitis) eye infections bacterial infections diverticulitis (irritation and infection of the big intestine) most cancers most cancers that impacts the lymph system melanoma immune issues that would have an effect on the lungs, pores and skin and lymph nodes (most commonly presenting as sarcoidosis) vasculitis (inflammation of blood vessels) tremor (shaking) neuropathy (dysfunction of the nerves) stroke listening to loss, buzzing sensation of coronary heart beating irregularly similar to skipped beats coronary heart problems that can trigger shortness of breath or ankle swelling heart attack a sac within the wall of a major artery, inflammation and clot of a vein, blockage of a blood vessel lung illnesses inflicting shortness of breath (including irritation) pulmonary embolism (blockage in an artery of the lung) pleural effusion (irregular collection of fluid within the pleural house) irritation of the pancreas which causes extreme ache in the abdomen and again difficulty in swallowing facial oedema (swelling of the face) gallbladder inflammation, gallbladder stones fatty liver night sweats scar irregular muscle breakdown 443 systemic lupus erythematosus (together with inflammation of skin, coronary heart, lung, joints and different organ systems) sleep interruptions impotence inflammations Rare (might affect up to 1 in 1,000 folks) leukaemia (most cancers affecting the blood and bone marrow) extreme allergic response with shock multiple sclerosis nerve problems (corresponding to eye nerve irritation and Guillain-Barre syndrome that will trigger muscle weakness, abnormal sensations, tingling in the arms and higher physique) heart stops pumping pulmonary fibrosis (scarring of the lung) intestinal perforation (hole in the intestine) hepatitis reactivation of hepatitis B autoimmune hepatitis (inflammation of the liver brought on by the physique's personal immune system) cutaneous vasculitis (inflammation of blood vessels within the pores and skin) Stevens-Johnson syndrome (early signs embrace malaise, fever, headache and rash) facial oedema (swelling of the face) related to allergic reactions erythema multiforme (inflammatory pores and skin rash) lupus-like syndrome angioedema (localized swelling of the pores and skin) lichenoid skin reaction (itchy reddish-purple skin rash) Not recognized (frequency cannot be estimated from the available knowledge) hepatosplenic T-cell lymphoma (a uncommon blood most cancers that's often deadly) Merkel cell carcinoma (a sort of pores and skin most cancers) liver failure worsening of a situation called dermatomyositis (seen as a pores and skin rash accompanying muscle weak spot) Some unwanted side effects observed with Humira could not have symptoms and may solely be discovered by way of blood checks. 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